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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS13C
All Species:
24.55
Human Site:
Y144
Identified Species:
67.5
UniProt:
Q709C8
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q709C8
NP_001018098.1
3753
422390
Y144
Y
G
L
E
N
F
V
Y
K
D
I
K
P
G
R
Chimpanzee
Pan troglodytes
XP_510458
3836
431033
Y226
Y
G
L
E
N
F
V
Y
K
D
I
K
P
G
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851912
3629
408076
Y144
Y
G
L
E
S
F
V
Y
K
D
I
K
P
G
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BX70
3748
420070
Y144
Y
G
L
E
N
L
L
Y
K
D
V
K
P
G
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511058
3801
426177
Y178
Y
G
L
E
T
L
V
Y
K
D
V
K
P
G
R
Chicken
Gallus gallus
XP_001233000
3758
422392
Y144
Y
G
L
E
S
L
I
Y
K
D
T
K
P
G
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922767
3699
412330
Y144
F
N
L
E
S
Y
V
Y
K
N
P
P
R
G
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192977
2470
271032
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q07878
3144
357831
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.9
N.A.
87
N.A.
86.4
N.A.
N.A.
77.2
68.7
N.A.
59.6
N.A.
N.A.
N.A.
N.A.
24.1
Protein Similarity:
100
97.4
N.A.
92
N.A.
93.3
N.A.
N.A.
87.6
82.9
N.A.
76.8
N.A.
N.A.
N.A.
N.A.
41
P-Site Identity:
100
100
N.A.
93.3
N.A.
80
N.A.
N.A.
80
73.3
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
N.A.
N.A.
86.6
86.6
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
67
0
0
0
0
0
% D
% Glu:
0
0
0
78
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
12
0
0
0
0
34
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
67
0
0
0
0
0
0
0
0
0
0
0
78
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
12
0
0
0
34
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
78
0
0
67
0
0
0
% K
% Leu:
0
0
78
0
0
34
12
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
12
0
0
34
0
0
0
0
12
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
12
12
67
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
78
% R
% Ser:
0
0
0
0
34
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
12
0
0
0
0
0
12
0
0
0
0
% T
% Val:
0
0
0
0
0
0
56
0
0
0
23
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
67
0
0
0
0
12
0
78
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _